Description

2-Chloro-6-(Trifluoromethyl)Benzyl Alcohol is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both chloro and trifluoromethyl substituents, provides unique electronic and steric properties that are critical for modulating the activity and physicochemical profile of target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor for novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Used in the research and development of advanced electronic materials, where its aromatic core and fluorine content contribute to desired electronic properties and stability.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and oxidation reactions to introduce the benzyl alcohol functional group with specific halogen/fluorine patterns.
• Chemical Research & Development: Essential for medicinal chemistry programs and structure-activity relationship (SAR) studies to explore new chemical entities.

Basic Information

Product Name	2-Chloro-6-(Trifluoromethyl)Benzyl Alcohol
CAS No.	886500-21-6
Molecular Formula	C8H6ClF3O
Molecular Weight	210.58 g/mol
Synonyms	(2-Chloro-6-(trifluoromethyl)phenyl)methanol; α-(Trifluoromethyl)-2-chloro-6-benzyl alcohol; 2-Chloro-α,α,α-trifluoro-o-tolyl alcohol; 1-Chloro-3-(hydroxymethyl)-2-(trifluoromethyl)benzene; 2-Chloro-6-trifluoromethylbenzyl alcohol; o-Chloro-α,α,α-trifluorobenzyl alcohol; Benzyl alcohol, 2-chloro-6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(Trifluoromethyl)Benzyl Alcohol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.