Description

2-Bromo-4-Chloro-6-Fluorophenol is a halogenated phenol derivative, a versatile and high-value building block in advanced organic synthesis. Its precise substitution pattern makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the halogen atoms contribute to bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated and halogenated aromatic cores, which are crucial for tuning the electro-optical properties of display and lighting materials.
• Polymer Modification: Acts as a monomer or functionalization agent for creating specialty polymers with enhanced flame retardancy, chemical resistance, or specific surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce functionalized phenolic groups into complex molecular architectures.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new chemical spaces and reaction methodologies in medicinal and materials chemistry.

Basic Information

Product Name	2-Bromo-4-Chloro-6-Fluorophenol
CAS No.	886499-88-3
Molecular Formula	C6H3BrClFO
Molecular Weight	225.44 g/mol
Synonyms	2-Bromo-4-chloro-6-fluorophenol; Phenol, 2-bromo-4-chloro-6-fluoro-; 4-Chloro-2-bromo-6-fluorophenol; 6-Fluoro-2-bromo-4-chlorophenol; 2-Br-4-Cl-6-F-Phenol; BCFP; (2-Bromo-4-chloro-6-fluorophenyl) alcohol
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-Chloro-6-Fluorophenol is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive applications like pharmaceutical R&D and electronic materials. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.