Description

(2,5-Dimethyl-5,6,7,8-Tetrahydro-Benzo[4,5]Thieno-[2,3-D]Pyrimidin-4-Ylamino)-Acetic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters as a critical building block in the synthesis of novel, targeted therapeutic agents, offering researchers and manufacturers a reliable and well-characterized starting material. It is primarily needed by pharmaceutical R&D teams and fine chemical producers engaged in developing kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
• Biochemical Research: Used as a reference standard or ligand in enzymatic assays and structure-activity relationship (SAR) studies.
• Medicinal Chemistry: Serves as a core scaffold for the design and optimization of new chemical entities (NCEs) with targeted biological activity.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex molecular architectures for advanced material science.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for pioneering studies in heterocyclic chemistry and drug discovery.

Basic Information

Product Name	(2,5-Dimethyl-5,6,7,8-Tetrahydro-Benzo[4,5]Thieno-[2,3-D]Pyrimidin-4-Ylamino)-Acetic Acid
CAS No.	886499-75-8
Molecular Formula	C₁₆H₁₉N₃O₂S
Molecular Weight	317.41 g/mol
Synonyms	4-[(Carboxymethyl)amino]-2,5-dimethyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine; N-[(2,5-Dimethyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)]glycine; Glycine, N-[(2,5-dimethyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)]-; 886499-75-8; BTTDP-AA; THBT-Pyrimidine acetic acid derivative
EINECS	Contact for details

Quality Control

Our (2,5-Dimethyl-5,6,7,8-Tetrahydro-Benzo[4,5]Thieno-[2,3-D]Pyrimidin-4-Ylamino)-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure compliance with research and development standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.