Description

4-(2,7-Dimethyl-5,6,7,8-Tetrahydro-Benzo[4,5]-Thieno[2,3-D]Pyrimidin-4-Ylamino)-Butyric Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a key building block in the synthesis of novel, targeted therapeutic agents, particularly in oncology and other disease-modifying treatments. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates, especially kinase inhibitors and other targeted therapies.
• Oncology Research: Used in the research and development of novel anti-cancer compounds due to its specific molecular scaffold.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Research: Employed as a tool compound or reference standard in biochemical assays to study specific biological pathways and protein interactions.
• Contract Manufacturing: Supplied to CDMOs for scale-up synthesis under current Good Manufacturing Practice (cGMP) conditions for clinical trial material production.

Basic Information

Product Name	4-(2,7-Dimethyl-5,6,7,8-Tetrahydro-Benzo[4,5]-Thieno[2,3-D]Pyrimidin-4-Ylamino)-Butyric Acid
CAS No.	886499-60-1
Molecular Formula	C₁₈H₂₃N₃O₂S
Molecular Weight	345.46 g/mol
Synonyms	4-[(2,7-Dimethyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)amino]butanoic acid; 4-(2,7-Dimethyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-ylamino)butyric acid; Butanoic acid, 4-[(2,7-dimethyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)amino]-; CAS 886499-60-1; BDBM50164995; SCHEMBL15506227; ZINC000003869756; AKOS025147310
EINECS	Contact for details

Quality Control

Our 4-(2,7-Dimethyl-5,6,7,8-Tetrahydro-Benzo[4,5]-Thieno[2,3-D]Pyrimidin-4-Ylamino)-Butyric Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.