Description

3-(7-Chloro-Quinazolin-4-Ylamino)-Propionic Acid CAS NO 886499-24-7 is a high-purity, synthetically derived quinazoline derivative, serving as a critical advanced pharmaceutical intermediate. Its molecular structure makes it a valuable building block for the research and development of targeted therapeutic agents. This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel drug candidates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of small-molecule kinase inhibitors and other targeted oncology drugs.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Research: Serves as a tool compound for studying enzyme inhibition and cellular signaling pathways.
• Fine Chemical Synthesis: Building block for creating complex heterocyclic compounds with potential biological activity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-scale production of active pharmaceutical ingredients (APIs).

Basic Information

Item	Detail
Product Name	3-(7-Chloro-Quinazolin-4-Ylamino)-Propionic Acid
CAS No.	886499-24-7
Molecular Formula	C₁₁H₁₀ClN₃O₂
Molecular Weight	251.67 g/mol
Synonyms	3-[(7-Chloroquinazolin-4-yl)amino]propanoic acid; 3-(7-Chloro-4-quinazolinyamino)propionic Acid; 886499-24-7; 7-Chloro-N-(2-carboxyethyl)-4-quinazolinamine; Propanoic acid, 3-[(7-chloro-4-quinazolinyl)amino]-; 3-(7-Chloro-quinazolin-4-ylamino)-propionic acid
EINECS	Contact for details

Quality Control

Our 3-(7-Chloro-Quinazolin-4-Ylamino)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to meet specific client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.