Description

3-Fluoro-4-(Trifluoromethoxy)Benzyl Alcohol is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound matters for its unique trifluoromethoxy and fluorine substituents, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of new active ingredients, as well as by material scientists exploring novel fluorinated polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Active Ingredient Precursor: Used to construct advanced herbicides, fungicides, and insecticides with enhanced environmental stability and efficacy.
• Liquid Crystal & OLED Material Development: Serves as a fluorinated core structure for creating high-performance electronic display and lighting materials.
• Fluorinated Polymer Monomer: Employed in the production of specialty polymers with improved chemical resistance and surface properties.
• Cross-Coupling Reactions: The benzyl alcohol group can be functionalized for use in Suzuki, Heck, and other palladium-catalyzed coupling reactions.
• Protecting Group Chemistry: Utilized in multi-step synthetic routes where the benzyl alcohol moiety requires selective protection and deprotection.

Basic Information

Item	Detail
Product Name	3-Fluoro-4-(Trifluoromethoxy)Benzyl Alcohol
CAS No.	886498-99-3
Molecular Formula	C8H6F4O2
Molecular Weight	210.13 g/mol
Synonyms	(3-Fluoro-4-(trifluoromethoxy)phenyl)methanol; 4-(Trifluoromethoxy)-3-fluorobenzyl Alcohol; 3-Fluoro-4-trifluoromethoxybenzyl Alcohol; α-Hydroxymethyl-3-fluoro-4-trifluoromethoxybenzene; 1-(Hydroxymethyl)-2-fluoro-4-(trifluoromethoxy)benzene; 886498-99-3; FC6H3(OCF3)CH2OH (where F is at the 3-position)
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(Trifluoromethoxy)Benzyl Alcohol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent oxidation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.