Description

2-Fluoro-5-(trifluoromethoxy)benzaldehyde is a high-purity fluorinated aromatic aldehyde building block, essential for advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethoxy substituents, makes it a critical intermediate for introducing specific electronic and steric properties into target molecules. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), improving performance and longevity.
• Advanced Polymer Chemistry: Employed to create specialty monomers and polymers with tailored properties such as chemical resistance, thermal stability, and specific optical characteristics.
• Cross-Coupling Reactions: A versatile substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Organic Synthesis & Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating novel fluorinated compounds.

Basic Information

Product Name	2-Fluoro-5-(trifluoromethoxy)benzaldehyde
CAS No.	886497-81-0
Molecular Formula	C8H4F4O2
Molecular Weight	208.11 g/mol
Synonyms	5-(Trifluoromethoxy)-2-fluorobenzaldehyde; 2-Fluoro-α,α,α-trifluoro-p-anisaldehyde; Benzaldehyde, 2-fluoro-5-(trifluoromethoxy)-; 2-Fluoro-5-(trifluoromethoxy)benzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(trifluoromethoxy)benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.