Description

2,3-Dichloro-6-Fluorobenzyl Bromide is a high-purity, multi-functional halogenated benzyl bromide building block essential for advanced organic synthesis. Its primary value lies in its reactive benzylic bromide site and strategically placed halogen substituents, enabling precise molecular construction in complex chemical environments. This intermediate is critically needed by R&D and production chemists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorochlorobenzyl motif.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the halogenated benzyl group contributes to biological activity and stability.
• Ligand and Catalyst Development: Serves as a versatile building block for constructing complex ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and halogenated structure.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to form new carbon-carbon bonds.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Item	Details
Product Name	2,3-Dichloro-6-Fluorobenzyl Bromide
CAS No.	886497-51-4
Molecular Formula	C7H4BrCl2F
Molecular Weight	257.91 g/mol
Synonyms	1-(Bromomethyl)-2,3-dichloro-6-fluorobenzene; (2,3-Dichloro-6-fluorophenyl)methyl Bromide; 2,3-Dichloro-6-fluoro-α-bromotoluene; 2,3-Dichloro-6-fluorobenzylbromide; α-Bromo-2,3-dichloro-6-fluorotoluene; 6-Fluoro-2,3-dichlorobenzyl Bromide
EINECS	Contact for details

Quality Control

Every batch of 2,3-Dichloro-6-Fluorobenzyl Bromide is manufactured under strict quality management protocols. We guarantee high chemical purity and lot-to-lot consistency through comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.