Description

3-Bromo-4-Trifluoromethoxyphenol is a halogenated phenol derivative featuring both bromine and a trifluoromethoxy substituent, making it a versatile and valuable synthetic intermediate. This compound is prized for its role in constructing complex molecules, particularly in the development of advanced materials and active pharmaceutical ingredients. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring halogenated aromatic motifs for bioactivity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the trifluoromethoxy group enhances lipophilicity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce specific properties into high-performance polymers.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create complex biaryl structures in medicinal chemistry.
• Chemical Research & Development: A valuable scaffold for discovering new compounds with potential biological activity in academic and industrial labs.

Basic Information

Product Name	3-Bromo-4-Trifluoromethoxyphenol
CAS No.	886496-88-4
Molecular Formula	C7H4BrF3O2
Molecular Weight	257.01 g/mol
Synonyms	3-Bromo-4-(trifluoromethoxy)phenol; Phenol, 3-bromo-4-(trifluoromethoxy)-; 4-Trifluoromethoxy-3-bromophenol; 3-Bromo-4-trifluoromethoxy-phenol; 886496-88-4; 3-Br-4-TFMP; 3-Bromo-4-(trifluoromethoxy)phen-1-ol
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Trifluoromethoxyphenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.