Description

2-(4-Fluorophenyl)-5-Methylpyrazolo[1,5-A]Pyrimidine-7-Carbohydrazide is a high-purity, advanced pharmaceutical intermediate with significant synthetic utility. This compound is valued for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting kinase inhibition and other enzyme-related pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its pyrazolopyrimidine core for biological activity.
• Organic Synthesis Building Block: Serves as a versatile scaffold for medicinal chemists to create diverse compound libraries for high-throughput screening (HTS).
• Biochemical Tool Compound: Employed in academic and industrial research to study biological mechanisms and validate new therapeutic targets.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized, non-commercial quantities under cGMP conditions.

Basic Information

Product Name	2-(4-Fluorophenyl)-5-Methylpyrazolo[1,5-A]Pyrimidine-7-Carbohydrazide
CAS No.	886495-98-3
Molecular Formula	C₁₄H₁₂FN₅O
Molecular Weight	285.28 g/mol
Synonyms	2-(4-Fluorophenyl)-5-methylpyrazolo[1,5-a]pyrimidine-7-carbohydrazide; 5-Methyl-2-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidine-7-carbohydrazide; 886495-98-3; Pyrazolo[1,5-a]pyrimidine-7-carbohydrazide, 2-(4-fluorophenyl)-5-methyl-; 2-(p-Fluorophenyl)-5-methylpyrazolo[1,5-a]pyrimidine-7-carboxylic acid hydrazide
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorophenyl)-5-Methylpyrazolo[1,5-A]Pyrimidine-7-Carbohydrazide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.