Description

Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-Aldehyde Trifluoroacetate Salt is a high-purity, synthetic peptide aldehyde derivative, specifically designed as a potent and selective protease inhibitor for biochemical research. This compound is critical for studying enzyme kinetics, cellular signaling pathways, and protein degradation mechanisms. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on drug discovery and proteomics. The trifluoroacetate salt form ensures enhanced solubility and stability for in-vitro applications.

Application

• Protease Inhibition Studies: Acts as a specific inhibitor for targeted proteases in enzymatic assays to elucidate biological functions.
• Drug Discovery & Development: Serves as a key pharmacophore or lead compound in the design of novel therapeutic agents targeting protease-related diseases.
• Biochemical Research: Used in vitro to investigate protein-protein interactions, signal transduction cascades, and apoptosis pathways.
• Cell Biology: Employed to modulate intracellular protease activity to study effects on cell cycle, differentiation, and disease models.
• Proteomics & Biomarker Discovery: A valuable tool for affinity purification and identification of specific protease targets from complex biological samples.
• Enzyme Mechanism Analysis: Provides insights into catalytic mechanisms and active site architecture of serine or cysteine proteases.

Basic Information

Product Name	Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-Aldehyde Trifluoroacetate Salt
CAS No.	886462-83-5
Molecular Formula	C94H155N19O25 • C2HF3O2
Molecular Weight	~1994.3 g/mol (Free base)
Synonyms	Ac-AAVALLPAVLLALLAPITD-CHO TFA Salt; Acetyl-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-Al TFA; Peptide Aldehyde Inhibitor; Proteasome Inhibitor Peptide; Suc-Leu-Leu-Val-Tyr-AMC related peptide aldehyde; Ac-AAVALLPAVLLALLAPITD-Aldehyde; N-Acetyl-AAVALLPAVLLALLAPITD-CHO Trifluoroacetate; Caspase Inhibitor Peptide Analog
EINECS	Contact for details

Quality Control

Our Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-Aldehyde Trifluoroacetate Salt is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and NMR for structural verification, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.