Description

1-(2,4-Dimethyl-Phenyl)-2,2,2-Trifluoro-Ethylamine is a high-purity, advanced pharmaceutical intermediate featuring a unique trifluoroethylamine moiety attached to a substituted aromatic ring. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders. It is primarily sought by research institutions, custom synthesis organizations, and pharmaceutical manufacturers engaged in the development of fluorinated drug candidates.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of fluorinated active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic electronic materials.
• Fluorine Chemistry Building Block: Essential for introducing the trifluoroethylamine functional group into complex molecular architectures in medicinal and synthetic chemistry.

Basic Information

Product Name	1-(2,4-Dimethyl-Phenyl)-2,2,2-Trifluoro-Ethylamine
CAS No.	886369-43-3
Molecular Formula	C10H12F3N
Molecular Weight	203.20 g/mol
Synonyms	α,α,α-Trifluoro-2,4-dimethylphenethylamine; 2,4-Dimethyl-α-(trifluoromethyl)benzeneethanamine; 1-(2,4-Dimethylphenyl)-2,2,2-trifluoroethanamine; 2,4-Dimethyl-α,α,α-trifluorophenethylamine; 2,2,2-Trifluoro-1-(2,4-dimethylphenyl)ethanamine; (2,4-Dimethylphenyl)(trifluoromethyl)methylamine; TFMPA derivative
EINECS	Contact for details

Quality Control

Our 1-(2,4-Dimethyl-Phenyl)-2,2,2-Trifluoro-Ethylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.