Description

1-(2,3-Dimethyl-Phenyl)-2,2,2-Trifluoro-Ethylamine is a specialized fluorinated aromatic amine building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of a substituted phenyl ring and a trifluoroethylamine moiety, which is critical for modulating the physicochemical and biological properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in creating molecules with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms can improve lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials to alter surface properties and electronic characteristics.
• Chemical Biology Probe: Utilized as a building block for developing fluorescent tags or molecular probes to study biological systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	1-(2,3-Dimethyl-Phenyl)-2,2,2-Trifluoro-Ethylamine
CAS No.	886369-40-0
Molecular Formula	C10H12F3N
Molecular Weight	203.20 g/mol
Synonyms	α,α,α-Trifluoro-2,3-dimethylphenethylamine; 2,3-Dimethyl-α,α,α-trifluorophenethylamine; 1-(2,3-Dimethylphenyl)-2,2,2-trifluoroethanamine; 2,2,2-Trifluoro-1-(2,3-dimethylphenyl)ethanamine; 886369-40-0; 2,3-Dimethyl-α-(trifluoromethyl)benzeneethanamine
EINECS	Contact for details

Quality Control

Our 1-(2,3-Dimethyl-Phenyl)-2,2,2-Trifluoro-Ethylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.