Description

5-Bromo-2-trifluoromethoxy-pyrimidine is a high-purity, multi-functional halogenated pyrimidine building block essential for modern synthetic chemistry. This compound is valued for its unique trifluoromethoxy and bromo substituents, which are critical for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including kinase inhibitors and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a precursor for creating specialty polymers and liquid crystals with tailored properties.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Bromo-2-trifluoromethoxy-pyrimidine
CAS No.	886365-69-1
Molecular Formula	C5H2BrF3N2O
Molecular Weight	242.98 g/mol
Synonyms	5-Bromo-2-(trifluoromethoxy)pyrimidine; 2-Trifluoromethoxy-5-bromopyrimidine; Pyrimidine, 5-bromo-2-(trifluoromethoxy)-; 886365-69-1; 5-Bromo-2-trifluoromethoxypyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-trifluoromethoxy-pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.