Description

3-Methoxy-2,4,5-Trifluorobenzylamine is a high-purity fluorinated benzylamine derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and methoxy substitution pattern makes it an invaluable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine atoms enhance bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic components for electronic display materials and organic light-emitting diodes (OLEDs).
• Functional Material Development: Employed in creating specialty polymers, ligands for catalysis, and advanced coatings that require specific fluorinated aromatic architectures.
• Chemical Research & Process Development: A versatile reagent for method development and scale-up in process chemistry within fine chemical and contract manufacturing organizations (CMOs).

Basic Information

Product Name	3-Methoxy-2,4,5-Trifluorobenzylamine
CAS No.	886362-79-4
Molecular Formula	C8H8F3NO
Molecular Weight	191.15 g/mol
Synonyms	2,4,5-Trifluoro-3-methoxybenzylamine; (2,4,5-Trifluoro-3-methoxyphenyl)methanamine; 3-Methoxy-2,4,5-trifluorobenzenemethanamine; Benzenemethanamine, 2,4,5-trifluoro-3-methoxy-; 886362-79-4; 2,4,5-Trifluoro-3-methoxybenzylamine HCl (salt form)
EINECS	Contact for details

Quality Control

Every batch of 3-Methoxy-2,4,5-Trifluorobenzylamine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.