Description

4-Chloro-6-(4-Methoxyphenyl)-2-(2-Pyridinyl)-5-Pyrimidinecarbonitrile is a high-value, multi-functional heterocyclic building block and advanced pharmaceutical intermediate. Its complex pyrimidine-pyridine core structure makes it a critical precursor in the synthesis of targeted small molecule therapeutics, particularly kinase inhibitors. This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the synthesis of advanced active ingredients for crop protection products.
• Chemical Biology Probe: Serves as a core scaffold for designing molecular probes to study biological pathways and enzyme functions.
• Organic Synthesis Building Block: Employed in complex multi-step organic syntheses to introduce functionalized pyrimidine motifs.
• Material Science Research: Investigated as a precursor for organic electronic materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Chloro-6-(4-Methoxyphenyl)-2-(2-Pyridinyl)-5-Pyrimidinecarbonitrile
CAS No.	886361-41-7
Molecular Formula	C₁₇H₁₁ClN₄O
Molecular Weight	322.75 g/mol
Synonyms	4-Chloro-6-(4-methoxyphenyl)-2-(pyridin-2-yl)pyrimidine-5-carbonitrile; 2-(4-Chloro-5-cyano-6-(4-methoxyphenyl)pyrimidin-2-yl)pyridine; 886361-41-7; 4-Chloro-6-(p-methoxyphenyl)-2-(2-pyridyl)-5-pyrimidinecarbonitrile; 5-Pyrimidinecarbonitrile, 4-chloro-6-(4-methoxyphenyl)-2-(2-pyridinyl)-; 4-Chloro-6-(4-methoxyphenyl)-2-(2-pyridyl)-5-cyanopyrimidine
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-6-(4-Methoxyphenyl)-2-(2-Pyridinyl)-5-Pyrimidinecarbonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.