Description

Methyl 2-Hydroxy-4-(Trifluoromethyl)Pyrimidine-5-Carboxylate is a high-purity pyrimidine derivative, a critical building block valued for its trifluoromethyl group and ester functionality. This compound is essential for research and development in advanced organic synthesis, particularly for creating novel molecules with enhanced properties. It is primarily sought after by pharmaceutical and agrochemical R&D teams for the development of new active ingredients and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Serves as a crucial precursor in the design and synthesis of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Organic Synthesis Building Block: Used in advanced organic chemistry for constructing complex heterocyclic systems, enabling the exploration of new chemical space in material science.
• Material Science Research: Investigated as a monomer or functional additive for developing specialty polymers and advanced materials with specific optical or electronic properties.
• Chemical Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Methyl 2-Hydroxy-4-(Trifluoromethyl)Pyrimidine-5-Carboxylate
CAS No.	886212-78-8
Molecular Formula	C7H5F3N2O3
Molecular Weight	222.12 g/mol
Synonyms	Methyl 2-hydroxy-4-(trifluoromethyl)pyrimidine-5-carboxylate; 5-Pyrimidinecarboxylic acid, 2-hydroxy-4-(trifluoromethyl)-, methyl ester; Methyl 2-oxo-4-(trifluoromethyl)-1,2-dihydropyrimidine-5-carboxylate; 2-Hydroxy-4-trifluoromethyl-pyrimidine-5-carboxylic acid methyl ester; 4-(Trifluoromethyl)-2-hydroxypyrimidine-5-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Hydroxy-4-(Trifluoromethyl)Pyrimidine-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.