Description

3-(2-(Trifluoromethyl)Phenyl)Benzyl Alcohol is a high-purity fluorinated aromatic alcohol building block of significant commercial interest. This compound matters for its role as a versatile intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where the trifluoromethyl group imparts desirable properties like metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate this unique fluorinated motif into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the CF3 group can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorinated aromatic units into polymer backbones, altering thermal stability, chemical resistance, and surface properties.
• Ligand & Catalyst Development: Useful in organometallic chemistry for creating specialized ligands used in asymmetric catalysis and cross-coupling reactions.
• Chemical Research (R&D): A valuable building block for medicinal chemistry, material science, and general organic synthesis research in academic and industrial laboratories.

Basic Information

Product Name	3-(2-(Trifluoromethyl)Phenyl)Benzyl Alcohol
CAS No.	885966-08-5
Molecular Formula	C14H11F3O
Molecular Weight	252.23 g/mol
Synonyms	[2-(Trifluoromethyl)phenyl][3-(hydroxymethyl)phenyl]methane; 1-(3-(Hydroxymethyl)phenyl)-2-(trifluoromethyl)benzene; α-(3-Hydroxymethylphenyl)-2-(trifluoromethyl)toluene; 3-[(2-Trifluoromethylphenyl)methyl]benzyl alcohol; 2'-(Trifluoromethyl)-[1,1'-biphenyl]-3-methanol; (3-((2-(Trifluoromethyl)phenyl)methyl)phenyl)methanol
EINECS	Contact for details

Quality Control

Our 3-(2-(Trifluoromethyl)Phenyl)Benzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability, consistency, and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.