Description

4-(2,6-Difluorophenyl)Benzyl Alcohol is a high-purity fluorinated aromatic alcohol building block. This compound is valued for its role as a versatile intermediate in the synthesis of advanced pharmaceutical and agrochemical active ingredients. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing complex molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: Key synthon in the development of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and fungicides, leveraging the difluorophenyl moiety for enhanced bioactivity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic displays and advanced optical materials.
• Organic Electronics: Building block for creating charge-transport or emissive layers in OLED (Organic Light-Emitting Diode) research.
• Cross-Coupling Reactions: The benzyl alcohol group can be functionalized, making it a useful substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions.
• Protecting Group Chemistry: The alcohol functionality can be used to protect or temporarily mask reactive sites during multi-step synthetic sequences.

Basic Information

Product Name	4-(2,6-Difluorophenyl)Benzyl Alcohol
CAS No.	885963-50-8
Molecular Formula	C13H10F2O
Molecular Weight	220.21 g/mol
Synonyms	[4-(2,6-Difluorophenyl)phenyl]methanol; (4-(2,6-Difluorophenyl)phenyl)methanol; 2,6-Difluoro-4'-(hydroxymethyl)biphenyl; 4'-(Hydroxymethyl)-2,6-difluorobiphenyl; 1-(2,6-Difluorophenyl)-4-(hydroxymethyl)benzene; α-(4-(2,6-Difluorophenyl)phenyl)methanol
EINECS	Contact for details

Quality Control

Our 4-(2,6-Difluorophenyl)Benzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.