Description

3-(2,4-Difluorophenyl)Benzyl Alcohol is a high-purity fluorinated aromatic alcohol building block. This compound is valued for its role as a versatile synthetic intermediate in advanced organic synthesis, enabling the introduction of a difluorophenyl-substituted benzyl moiety. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the difluorophenyl group can enhance biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies, contributing to improved electro-optical properties.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and charge-transport materials for OLEDs and other electronic devices.
• Cross-Coupling Reactions: The benzyl alcohol group can be functionalized or used in palladium-catalyzed cross-coupling reactions to construct complex molecular architectures.
• Protecting Group Chemistry: Acts as a starting material for reagents used in selective protection and deprotection strategies during multi-step syntheses.

Basic Information

Product Name	3-(2,4-Difluorophenyl)Benzyl Alcohol
CAS No.	885963-44-0
Molecular Formula	C13H10F2O
Molecular Weight	220.22 g/mol
Synonyms	[3-(2,4-Difluorophenyl)phenyl]methanol; 1-(2,4-Difluorophenyl)-3-(hydroxymethyl)benzene; (3-(2,4-Difluorophenyl)phenyl)methanol; 2,4-Difluoro-3'-hydroxymethylbiphenyl; α-(2,4-Difluorophenyl)-m-tolylmethanol; m-((2,4-Difluorophenyl)hydroxymethyl)benzene
EINECS	Contact for details

Quality Control

Our 3-(2,4-Difluorophenyl)Benzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.