Description

4-Benzyloxy-5-Bromo-2-(4-Methylpiperazin-1-Yl)-Pyrimidine is a high-purity, functionalized pyrimidine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical pharmaceutical intermediate for the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of new therapeutic agents, particularly within medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new molecular entities.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of diverse pyrimidine-based compound libraries.
• Biochemical Research: Potential use as a tool compound or probe in biochemical assays to study specific biological pathways and enzyme interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	4-Benzyloxy-5-Bromo-2-(4-Methylpiperazin-1-Yl)-Pyrimidine
CAS No.	885952-24-9
Molecular Formula	C16H19BrN4O
Molecular Weight	363.26 g/mol
Synonyms	5-Bromo-4-(benzyloxy)-2-(4-methyl-1-piperazinyl)pyrimidine; 2-(4-Methylpiperazin-1-yl)-5-bromo-4-(phenylmethoxy)pyrimidine; 4-Benzyloxy-5-bromo-2-(4-methylpiperazin-1-yl)pyrimidine; 885952-24-9; 4-(Benzyloxy)-5-bromo-2-(4-methylpiperazin-1-yl)pyrimidine; 5-Bromo-4-(benzyloxy)-2-(4-methylpiperazin-1-yl)pyrimidine; 4-(Benzyloxy)-5-bromo-2-(N-methylpiperazinyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Benzyloxy-5-Bromo-2-(4-Methylpiperazin-1-Yl)-Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports its use in demanding applications, including pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.