Description

4-Benzyloxy-5-Bromo-2-(Piperidin-1-Yl)Pyrimidine is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is valued for its role as a key building block in medicinal chemistry, enabling the development of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for oncology, virology, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel small-molecule drug candidates, particularly in kinase inhibitor research.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic entities.
• Process Chemistry Development: Serves as a key starting material (KSM) or intermediate in scaling up API synthesis for clinical trials and commercial manufacturing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for exploratory research in heterocyclic and organic chemistry.

Basic Information

Product Name	4-Benzyloxy-5-Bromo-2-(Piperidin-1-Yl)Pyrimidine
CAS No.	885952-22-7
Molecular Formula	C16H18BrN3O
Molecular Weight	348.24 g/mol
Synonyms	5-Bromo-4-(phenylmethoxy)-2-(1-piperidinyl)pyrimidine; 4-(Benzyloxy)-5-bromo-2-piperidin-1-ylpyrimidine; 2-(Piperidin-1-yl)-4-(benzyloxy)-5-bromopyrimidine; 885952-22-7; 4-Benzyloxy-5-bromo-2-piperidin-1-yl-pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Benzyloxy-5-Bromo-2-(Piperidin-1-Yl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results. We support development and commercial projects requiring material suitable for use under cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.