Description

(4-Aminophenyl)[4-(2-Pyrimidinyl)Piperazino]Methanone is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold. This compound is of significant commercial interest for its role as a key building block in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology applications. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers seeking reliable, high-quality intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, especially those targeting neurological receptors.
• Chemical Research & Development: Serves as a versatile building block for medicinal chemists exploring new chemical entities and structure-activity relationships (SAR).
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex APIs for preclinical and clinical studies.
• Biochemical Research: Employed in biochemical assays and as a tool compound for studying specific biological pathways and enzyme interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under GMP or non-GMP conditions.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	(4-Aminophenyl)[4-(2-Pyrimidinyl)Piperazino]Methanone
CAS No.	885949-72-4
Molecular Formula	C15H17N5O
Molecular Weight	283.33 g/mol
Synonyms	4-Amino-N-(4-pyrimidin-2-ylpiperazin-1-yl)benzamide; 1-(4-Aminobenzoyl)-4-(pyrimidin-2-yl)piperazine; 4-Amino-N-[4-(2-pyrimidinyl)-1-piperazinyl]benzamide; (4-Aminobenzoyl)-4-(2-pyrimidyl)piperazine; 885949-72-4; 4-Aminophenyl(4-pyrimidin-2-ylpiperazin-1-yl)methanone
EINECS	Contact for details

Quality Control

Our (4-Aminophenyl)[4-(2-Pyrimidinyl)Piperazino]Methanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support development and commercial projects with material suitable for research use or produced under higher standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.