Description

5-[(4-Methylphenyl)Sulfonyl]-2-Phenyl-4-Pyrimidinol is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery. It is primarily needed by R&D laboratories, pharmaceutical manufacturers, and fine chemical producers developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor research.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Used in the construction of complex heterocyclic compounds for agrochemical and material science applications.
• Biochemical Research: Employed as a tool compound or reference standard in biochemical assays and target validation studies.

Basic Information

Product Name	5-[(4-Methylphenyl)Sulfonyl]-2-Phenyl-4-Pyrimidinol
CAS No.	885949-45-1
Molecular Formula	C17H14N2O3S
Molecular Weight	326.37 g/mol
Synonyms	5-(p-Tolylsulfonyl)-2-phenyl-4-pyrimidinol; 2-Phenyl-5-(4-methylphenyl)sulfonyl-4-pyrimidinol; 5-(4-Methylbenzenesulfonyl)-2-phenylpyrimidin-4-ol; 4-Pyrimidinol, 5-[(4-methylphenyl)sulfonyl]-2-phenyl-; 5-(p-Toluenesulfonyl)-2-phenyl-4(1H)-pyrimidinone; 5-(4-Methylphenylsulfonyl)-2-phenyl-4(3H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our 5-[(4-Methylphenyl)Sulfonyl]-2-Phenyl-4-Pyrimidinol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.