Description

2-(4-((2-Chloro-4-Morpholinothieno[3,2-D]Pyrimidin-6-Yl)Methyl)Piperazin-1-Yl)Ethanol is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of targeted kinase inhibitors. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutic agents for oncology and other disease areas.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potent and selective kinase inhibitors for cancer therapy.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs targeting specific enzymatic pathways.
• Preclinical Development: Serves as a critical precursor for producing candidate drug molecules for in vitro and in vivo biological evaluation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of novel chemical entities.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery.
• Biochemical Probe Development: Potential use in creating tool compounds for studying cellular signaling mechanisms.

Basic Information

Product Name	2-(4-((2-Chloro-4-Morpholinothieno[3,2-D]Pyrimidin-6-Yl)Methyl)Piperazin-1-Yl)Ethanol
CAS No.	885675-75-2
Molecular Formula	C17H24ClN5O2S
Molecular Weight	397.92 g/mol
Synonyms	2-[4-[[2-Chloro-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl]piperazin-1-yl]ethanol; 2-Chloro-4-morpholino-6-[(4-(2-hydroxyethyl)piperazin-1-yl)methyl]thieno[3,2-d]pyrimidine; 885675-75-2; UNII-9J8F0C8Y4P; Thienopyrimidine derivative intermediate; Kinase inhibitor intermediate; 9J8F0C8Y4P
EINECS	Contact for details

Quality Control

Every batch of 2-(4-((2-Chloro-4-Morpholinothieno[3,2-D]Pyrimidin-6-Yl)Methyl)Piperazin-1-Yl)Ethanol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.