Description

4-(2-Chloro-6-((4-Methylpiperazin-1-Yl)Methyl)Thieno[3,2-D]Pyrimidin-4-Yl)Morpholine is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of investigational new drugs, particularly kinase inhibitors targeting various oncology pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of drug candidates.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme function and inhibition mechanisms in academic and industrial research settings.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client drug discovery programs.

Basic Information

Product Name	4-(2-Chloro-6-((4-Methylpiperazin-1-Yl)Methyl)Thieno[3,2-D]Pyrimidin-4-Yl)Morpholine
CAS No.	885618-54-2
Molecular Formula	C16H22ClN5OS
Molecular Weight	367.90 g/mol
Synonyms	4-(2-Chloro-6-((4-methylpiperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine; 4-Morpholino-2-chloro-6-[(4-methyl-1-piperazinyl)methyl]thieno[3,2-d]pyrimidine; Thieno[3,2-d]pyrimidine, 4-(2-chloro-6-((4-methyl-1-piperazinyl)methyl)-4-morpholino-; UNII-9F6H8VK2QN; 885618-54-2; 4-(2-Chloro-6-((4-methylpiperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine
EINECS	Contact for details

Quality Control

Our 4-(2-Chloro-6-((4-Methylpiperazin-1-Yl)Methyl)Thieno[3,2-D]Pyrimidin-4-Yl)Morpholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities to meet the exacting standards of pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.