Description

Prolylglycine Hydrochloride is a high-purity, protected dipeptide building block essential for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise control over peptide sequence and structure, particularly for creating complex bioactive molecules. It serves as a key intermediate in pharmaceutical R&D for developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: A crucial building block for the solid-phase and solution-phase synthesis of therapeutic peptides targeting various diseases.
• Biochemical Research: Used in studying enzyme-substrate interactions, peptide folding, and as a standard in analytical method development.
• Cosmeceutical Peptide Synthesis: Incorporated into the production of specialized peptides for advanced skincare and anti-aging formulations.
• Diagnostic Reagent Development: Serves as a component in synthesizing peptide-based biomarkers and assay reagents.
• Academic & Institutional Research: Provides a reliable, high-quality reagent for universities and research institutes exploring peptide chemistry and biology.

Basic Information

Product Name	Prolylglycine Hydrochloride
CAS No.	885459-11-0
Molecular Formula	C7H13N3O3 • HCl
Molecular Weight	223.66 g/mol (Free base: 187.20)
Synonyms	H-Pro-Gly-OH • HCl; L-Prolylglycine Hydrochloride; Pro-Gly dipeptide hydrochloride; (S)-2-(Pyrrolidine-2-carboxamido)acetic acid hydrochloride; N-[(2S)-Pyrrolidin-2-ylcarbonyl]glycine hydrochloride; Boc-Pro-Gly-OH deprotected salt; PG-OH • HCl
EINECS	Contact for details

Quality Control

Our Prolylglycine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for peptide synthesis. A Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Chiral Purity	≥99.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.