Description

5,6-Difluoro-1H-Indazole-3-Carbonitrile is a high-value fluorinated indazole derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its core value lies in its unique molecular scaffold, which is essential for constructing complex molecules with targeted biological activity. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and oncology research programs.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the biological activity of the difluoro-indazole core.
• Chemical Biology Probe Synthesis: Employed to create specialized molecular tools for studying enzyme function and cellular pathways.
• Material Science Research: Investigated as a precursor for advanced organic electronic materials due to its electron-deficient aromatic system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client-specific projects.

Basic Information

Product Name	5,6-Difluoro-1H-Indazole-3-Carbonitrile
CAS No.	885278-36-4
Molecular Formula	C8H3F2N3
Molecular Weight	179.13 g/mol
Synonyms	5,6-Difluoro-1H-indazole-3-carbonitrile; 3-Cyano-5,6-difluoro-1H-indazole; 5,6-Difluoroindazole-3-carbonitrile; 1H-Indazole-3-carbonitrile, 5,6-difluoro-; 885278-36-4
EINECS	Contact for details

Quality Control

Our 5,6-Difluoro-1H-Indazole-3-Carbonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.