Description

4-Chloro-2-(4-Chloro-Phenyl)-6-Fluoro-Quinazoline is a high-purity, multi-halogenated quinazoline derivative, a critical building block in advanced organic synthesis. Its precise molecular architecture makes it an essential intermediate for developing novel, high-value compounds. This product is primarily targeted at research and development teams in the pharmaceutical and agrochemical industries, where it serves as a key precursor for creating active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging its halogenated quinazoline core.
• Material Science Research: Serves as a precursor for organic electronic materials and photoactive compounds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: An important starting material for custom synthesis projects requiring complex, halogenated heterocycles.

Basic Information

Product Name	4-Chloro-2-(4-Chloro-Phenyl)-6-Fluoro-Quinazoline
CAS No.	885277-63-4
Molecular Formula	C14H7Cl2FN2
Molecular Weight	293.12 g/mol
Synonyms	2,4-Dichloro-6-fluoroquinazoline; 6-Fluoro-2,4-dichloroquinazoline; 4-Chloro-2-(4-chlorophenyl)-6-fluoroquinazoline; 885277-63-4; Quinazoline, 4-chloro-2-(4-chlorophenyl)-6-fluoro-; SCHEMBL2184221; AKOS040759232; FT-0773297
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(4-Chloro-Phenyl)-6-Fluoro-Quinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports applications in GMP and research-grade environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.