Description

4-Chloro-7-Fluoro-2-(2-Fluoro-Phenyl)-Quinazoline is a high-purity, multi-functional heterocyclic building block of significant commercial and research interest. Its unique quinazoline core, substituted with halogen atoms at strategic positions, makes it a critical intermediate in modern synthetic chemistry. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in developing novel herbicides and fungicides due to its bioactive quinazoline scaffold.
• Material Science: Serves as a building block for organic electronic materials and liquid crystals.
• Chemical Synthesis: An essential reagent for constructing complex heterocyclic compounds in medicinal chemistry.
• Academic & Contract Research: Utilized in university and CRO laboratories for drug discovery programs and methodological studies.

Basic Information

Product Name	4-Chloro-7-Fluoro-2-(2-Fluoro-Phenyl)-Quinazoline
CAS No.	885277-58-7
Molecular Formula	C14H7ClF2N2
Molecular Weight	276.67 g/mol
Synonyms	2-(2-Fluorophenyl)-4-chloro-7-fluoroquinazoline; 4-Chloro-7-fluoro-2-(2-fluorophenyl)quinazoline; Quinazoline, 4-chloro-7-fluoro-2-(2-fluorophenyl)-; 885277-58-7; 4-Chloro-7-fluoro-2-(o-fluorophenyl)quinazoline; 2-(2-Fluorophenyl)-4-chloro-7-fluoro-quinazoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-7-Fluoro-2-(2-Fluoro-Phenyl)-Quinazoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC/GC profiles, to support your regulatory and R&D requirements. Our standard grade meets typical research and intermediate synthesis specifications, with custom purity levels available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.