Description

4-Chloro-2-(2-Fluoro-Phenyl)-6-Methyl-Quinazoline is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesis and scale-up projects.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its quinazoline core for biological activity.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization and the creation of complex molecular libraries for screening.
• Academic & Institutional R&D: Employed in university and research institute laboratories for medicinal chemistry studies and novel reaction pathway exploration.
• Material Science: Investigated for potential applications in the development of organic electronic materials due to its conjugated system.

Basic Information

Product Name	4-Chloro-2-(2-Fluoro-Phenyl)-6-Methyl-Quinazoline
CAS No.	885277-53-2
Molecular Formula	C15H10ClFN2
Molecular Weight	272.70 g/mol
Synonyms	4-Chloro-2-(2-fluorophenyl)-6-methylquinazoline; 2-(2-Fluorophenyl)-4-chloro-6-methylquinazoline; 6-Methyl-4-chloro-2-(2-fluorophenyl)quinazoline; Quinazoline, 4-chloro-2-(2-fluorophenyl)-6-methyl-; 885277-53-2; 4-Chloro-2-(o-fluorophenyl)-6-methylquinazoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(2-Fluoro-Phenyl)-6-Methyl-Quinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for every shipment, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.