Description

6-(Bromomethyl)Thieno[2,3-D]Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate featuring a reactive bromomethyl group on a fused thienopyrimidine scaffold. This compound is a critical building block in medicinal chemistry, enabling the synthesis of targeted small molecule inhibitors for therapeutic applications. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other novel drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent kinase inhibitors targeting various disease pathways.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Bioconjugation & Probe Development: The reactive bromomethyl group allows for functionalization and conjugation to biomolecules or solid supports for chemical biology applications.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic libraries for high-throughput screening.
• Oncology Drug Development: Serves as a core scaffold for developing targeted cancer therapies.

Basic Information

Product Name	6-(Bromomethyl)Thieno[2,3-D]Pyrimidin-4-Amine
CAS No.	885269-04-5
Molecular Formula	C7H6BrN3S
Molecular Weight	244.11 g/mol
Synonyms	6-(Bromomethyl)-4-aminothieno[2,3-d]pyrimidine; 4-Amino-6-(bromomethyl)thieno[2,3-d]pyrimidine; Thieno[2,3-d]pyrimidin-4-amine, 6-(bromomethyl)-; 6-Bromomethyl-4-aminothieno[2,3-d]pyrimidine; CAS 885269-04-5; 6-(Bromomethyl)-4-thieno[2,3-d]pyrimidinamine
EINECS	Contact for details

Quality Control

Our 6-(Bromomethyl)Thieno[2,3-D]Pyrimidin-4-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.