Description

(3S)-n-(2,4-Dichlorobenzyl)-1-(5-Bromopyrimidin-2-Yl)Pyrrolidinyl-3-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a defined stereochemistry. This compound is valued for its role as a critical building block in the synthesis of novel, targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical companies engaged in the development of small-molecule drugs, particularly within oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Preclinical Development: Employed in the synthesis of candidate compounds for pharmacological and toxicological evaluation.
• Chemical Biology Probes: Utilized in the design of molecular probes to study specific biological pathways and target validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	(3S)-n-(2,4-Dichlorobenzyl)-1-(5-Bromopyrimidin-2-Yl)Pyrrolidinyl-3-Amine Hydrochloride
CAS No.	885104-09-6
Molecular Formula	C15H16BrCl2N5•HCl
Molecular Weight	467.59 g/mol
Synonyms	(3S)-N-[(2,4-Dichlorophenyl)methyl]-1-(5-bromo-2-pyrimidinyl)-3-pyrrolidinamine hydrochloride; (S)-N-(2,4-Dichlorobenzyl)-1-(5-bromopyrimidin-2-yl)pyrrolidin-3-amine hydrochloride; 1-(5-Bromopyrimidin-2-yl)-N-[(2,4-dichlorophenyl)methyl]-L-prolinamide hydrochloride; CAS 885104-09-6; 885104-09-6
EINECS	Contact for details

Quality Control

Our (3S)-n-(2,4-Dichlorobenzyl)-1-(5-Bromopyrimidin-2-Yl)Pyrrolidinyl-3-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.