Description

2-Pyrimidinamine, 5-Ethynyl-n-Methyl- (9Ci) is a specialized heterocyclic building block featuring a pyrimidine core substituted with an ethynyl group and a methylamino moiety. This compound is of significant value in advanced organic synthesis and pharmaceutical research, where its unique structure enables the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry and as a key intermediate for functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and combinatorial chemistry libraries due to its reactive ethynyl handle for click chemistry.
• Agrochemical Development: Employed as a precursor in the research and synthesis of new active ingredients for crop protection.
• Material Science: Acts as a monomer or cross-linking agent in the development of advanced polymers and functional organic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Academic & Institutional Research: A valuable reagent for universities and research institutes exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-Pyrimidinamine, 5-Ethynyl-n-Methyl- (9Ci)
CAS No.	884603-50-3
Molecular Formula	C7H7N3
Molecular Weight	133.15 g/mol
Synonyms	5-Ethynyl-N-methylpyrimidin-2-amine; N-Methyl-5-ethynylpyrimidin-2-amine; 5-Ethynyl-2-(methylamino)pyrimidine; 2-Amino-5-ethynyl-N-methylpyrimidine; 5-Ethynyl-2-methylaminopyrimidine; 884603-50-3; 5-Ethynyl-N-methyl-2-pyrimidinamine
EINECS	Contact for details

Quality Control

Our 2-Pyrimidinamine, 5-Ethynyl-n-Methyl- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports compliance with relevant research and development standards, ensuring reliable performance in your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.