Description

2-Fluoro-5-Formyl-3-Picoline is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a formyl group and a fluorine atom on the pyridine ring, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used to develop novel pesticides and herbicides, where the fluorine atom enhances biological activity, metabolic stability, and lipophilicity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced organic electronic materials, such as fluorinated polymers and small molecules for OLEDs.
• Chemical Biology Probes: Utilized to synthesize fluorinated probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Fluoro-5-Formyl-3-Picoline
CAS No.	884495-04-9
Molecular Formula	C7H6FNO
Molecular Weight	139.13 g/mol
Synonyms	5-Formyl-2-fluoro-3-picoline; 2-Fluoro-5-formyl-3-methylpyridine; 3-Methyl-2-fluoro-5-pyridinecarboxaldehyde; 2-Fluoro-3-methyl-5-pyridinecarbaldehyde; 2-Fluoro-5-formyl-3-picoline; 884495-04-9; 3-Picoline, 2-fluoro-5-formyl-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Formyl-3-Picoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.