Description

2-(4-Methyl-Piperidin-1-Yl)-Pyrimidine-5-Carboxylic Acid is a high-purity, heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular architecture, featuring both piperidine and pyrimidine motifs, makes it an invaluable intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical development teams engaged in medicinal chemistry and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in therapeutic areas targeting the central nervous system.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a crucial precursor in the multi-step synthesis of complex target molecules for preclinical and clinical evaluation.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Agrochemical Research: Potential intermediate in the development of novel crop protection agents and pesticides.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for fundamental organic synthesis and method development projects.

Basic Information

Item	Details
Product Name	2-(4-Methyl-Piperidin-1-Yl)-Pyrimidine-5-Carboxylic Acid
CAS No.	883543-77-9
Molecular Formula	C11H15N3O2
Molecular Weight	221.26 g/mol
Synonyms	2-(4-Methylpiperidin-1-yl)pyrimidine-5-carboxylic acid; 2-(4-Methyl-1-piperidinyl)-5-pyrimidinecarboxylic acid; 5-Pyrimidinecarboxylic acid, 2-(4-methyl-1-piperidinyl)-; 883543-77-9; 2-(4-Methylpiperidino)pyrimidine-5-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Methyl-Piperidin-1-Yl)-Pyrimidine-5-Carboxylic Acid is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.