Description

2-(4-Methyl-Piperidin-1-Yl)-Pyrimidine-5-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate featuring a unique pyrimidine-piperidine hybrid structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization due to its reactive aldehyde group and heterocyclic core.
• Agrochemical Research: Serves as a synthetic intermediate in the development of new crop protection agents and herbicides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for target identification and validation in biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up activities.
• Academic Research: Employed in university and institutional laboratories for heterocyclic chemistry and synthetic methodology development.

Basic Information

Product Name	2-(4-Methyl-Piperidin-1-Yl)-Pyrimidine-5-Carbaldehyde
CAS No.	883543-62-2
Molecular Formula	C11H15N3O
Molecular Weight	205.26 g/mol
Synonyms	2-(4-Methylpiperidin-1-yl)pyrimidine-5-carboxaldehyde; 5-Formyl-2-(4-methyl-1-piperidinyl)pyrimidine; 2-(4-Methyl-1-piperazinyl)pyrimidine-5-carbaldehyde (common misnomer); 883543-62-2; Pyrimidine-5-carbaldehyde, 2-(4-methyl-1-piperidinyl)-; 2-(4-Methylpiperidino)pyrimidine-5-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-(4-Methyl-Piperidin-1-Yl)-Pyrimidine-5-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications, and our quality commitment ensures reliable supply for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. The compound is easily oxidized and light-sensitive. Allow the sealed container to reach room temperature before opening to prevent moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.