Description

4-Ethoxy-3,5-Difluorobenzaldehyde is a versatile fluorinated aromatic aldehyde building block of significant importance in advanced organic synthesis. Its core value lies in the strategic placement of fluorine and ethoxy substituents, which enables precise tuning of electronic and steric properties in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the difluoroethoxy moiety contributes to enhanced bioactivity and environmental stability.
• Liquid Crystal Materials: Serves as a core building block for fluorinated liquid crystals, which are critical for high-performance displays (LCDs).
• Organic Electronic Materials: Employed in the research and production of organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Chemical Research & Development: A valuable reagent for exploring new reactions in fluoroorganic chemistry and for creating specialized ligands and catalysts.
• Fine Chemical Production: Utilized in the multi-step synthesis of dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	4-Ethoxy-3,5-Difluorobenzaldehyde
CAS No.	883536-06-9
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	3,5-Difluoro-4-ethoxybenzaldehyde; 4-Ethoxy-3,5-difluorobenzenecarboxaldehyde; Benzaldehyde, 3,5-difluoro-4-ethoxy-; 883536-06-9; 4-Ethoxy-3,5-difluoro-benzaldehyde
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-3,5-Difluorobenzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider an inert atmosphere (e.g., nitrogen or argon). Keep away from strong oxidizing agents, strong bases, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 98.5%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Maximum Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.