Description

tert-Butyl (5-Bromopyrimidin-2-Yl)Carbamate is a high-purity, protected pyrimidine building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling precise molecular modifications. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, antiviral agents, and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Chemical Biology: Serves as a versatile precursor for creating molecular probes and labeled compounds for biological studies.
• Material Science: Potential monomer or precursor for functional polymers and advanced organic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Custom Synthesis: Foundation for contract research organizations (CROs) and CDMOs to produce bespoke compounds for client projects.

Basic Information

Product Name	tert-Butyl (5-Bromopyrimidin-2-Yl)Carbamate
CAS No.	883231-23-0
Molecular Formula	C9H12BrN3O2
Molecular Weight	274.12 g/mol
Synonyms	5-Bromo-2-pyrimidinamine, N-BOC derivative; 2-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-bromopyrimidine; tert-Butyl N-(5-bromopyrimidin-2-yl)carbamate; Boc-5-Bromopyrimidin-2-amine; 5-Bromo-2-((tert-butoxycarbonyl)amino)pyrimidine; N-Boc-5-bromopyrimidin-2-amine; 2-Amino-5-bromopyrimidine N-Boc protected; (5-Bromo-pyrimidin-2-yl)-carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (5-Bromopyrimidin-2-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC Area %)	≥ 98.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.