Description

5-Bromo-2-(1H-Imidazol-1-yl)pyrimidine is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its dual functionality, serving as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides that require specific heterocyclic cores for bioactivity.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or linker in the design of chemical probes and activity-based protein profiling (ABPP) reagents.
• Material Science Research: Serves as a precursor for the synthesis of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional laboratories for methodological development in cross-coupling reactions and heterocyclic chemistry.

Basic Information

Product Name	5-Bromo-2-(1H-Imidazol-1-yl)pyrimidine
CAS No.	883230-68-0
Molecular Formula	C7H5BrN4
Molecular Weight	225.05 g/mol
Synonyms	5-Bromo-2-(imidazol-1-yl)pyrimidine; 2-(1H-Imidazol-1-yl)-5-bromopyrimidine; 5-Bromo-2-imidazol-1-ylpyrimidine; Pyrimidine, 5-bromo-2-(1H-imidazol-1-yl)-; 883230-68-0; 5-Bromo-2-(1H-imidazol-1-yl)pyrimidine; 5-Bromo-2-(1H-imidazol-1-yl)pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(1H-Imidazol-1-yl)pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.