Description

6-Chloro-N4-Pyridin-3-Ylmethyl-Pyrimidine-4,5-Diamine is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 882765-46-0. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), valued for its precise molecular structure that enables targeted drug development. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the discovery and production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly in oncology and antiviral research pipelines.
• Chemical Synthesis Building Block: Used in organic synthesis for constructing pyrimidine and pyridine-based heterocyclic compounds.
• Research & Development (R&D): Essential for medicinal chemistry research in academic and industrial laboratories for structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Manufacturing: Serves as a critical intermediate in the multi-step production of final API substances under GMP conditions.
• Contract Manufacturing (CMO/CDMO): Supplied to contract development and manufacturing organizations for custom synthesis projects.
• Biochemical Research: Potential use as a tool compound or inhibitor in biochemical and pharmacological assays.

Basic Information

Item	Details
Product Name	6-Chloro-N4-Pyridin-3-Ylmethyl-Pyrimidine-4,5-Diamine
CAS No.	882765-46-0
Molecular Formula	C10H11ClN6
Molecular Weight	250.69 g/mol
Synonyms	6-Chloro-N4-(pyridin-3-ylmethyl)pyrimidine-4,5-diamine; 4,5-Diamino-6-chloro-N-(3-pyridinylmethyl)-2-pyrimidinamine; 6-Chloro-N-(3-pyridylmethyl)pyrimidine-4,5-diamine; 882765-46-0; 6-Chloro-N4-(3-pyridinylmethyl)-4,5-pyrimidinediamine; 4,5-Pyrimidinediamine, 6-chloro-N-(3-pyridinylmethyl)-; 6-Chloro-N-(pyridin-3-ylmethyl)pyrimidine-4,5-diamine
EINECS	Contact for details

Quality Control

Our 6-Chloro-N4-Pyridin-3-Ylmethyl-Pyrimidine-4,5-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.