Description

(2-Pyridylmethyl)Sulfonyl Chloride Triflate is a specialized organosulfur reagent featuring a reactive sulfonyl chloride group activated by a triflate moiety. This compound matters for its high reactivity as a sulfonylation agent, enabling the efficient synthesis of sulfonamides and sulfonate esters under mild conditions. It is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for constructing complex molecules and developing active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including protease inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides that incorporate sulfonyl functional groups for enhanced activity.
• Chemical Biology Probes: Employed to label proteins and biomolecules via sulfonylation reactions for studying biological pathways.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers with sulfone linkages.
• Material Science Research: Utilized in surface modification and the creation of advanced organic materials with specific electronic properties.
• Catalyst Ligand Synthesis: Serves as a precursor for synthesizing sophisticated ligands used in transition metal catalysis.

Basic Information

Product Name	(2-Pyridylmethyl)Sulfonyl Chloride Triflate
CAS No.	882564-09-2
Molecular Formula	C7H6ClF3NO4S2
Molecular Weight	333.70 g/mol
Synonyms	2-(Chlorosulfonylmethyl)pyridine Trifluoromethanesulfonate; Pyridine-2-methanesulfonyl Chloride Triflate; 2-Pyridylmethanesulfonyl Chloride Triflate; (Pyridin-2-ylmethyl)sulfonyl Chloride Trifluoromethanesulfonate; 2-(Chlorosulfonylmethyl)pyridinium Triflate; (2-Pyridyl)methanesulfonyl Chloride Triflate; PymesyCl Triflate
EINECS	Contact for details

Quality Control

Our (2-Pyridylmethyl)Sulfonyl Chloride Triflate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.