Description

1-(6-Chloro-5-Nitro-4-Pyrimidinyl)-1,2,3,4-Tetrahydroquinoline is a high-value, heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its unique fused pyrimidine-quinoline structure makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for its role in creating molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in developing new generation pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Chemical Synthesis Building Block: Employed in organic synthesis to construct complex polycyclic frameworks for material science and catalysis research.
• Biochemical Probe Development: Serves as a scaffold for creating molecular probes and inhibitors used in biochemical and pharmacological studies.

Basic Information

Product Name	1-(6-Chloro-5-Nitro-4-Pyrimidinyl)-1,2,3,4-Tetrahydroquinoline
CAS No.	882276-62-2
Molecular Formula	C₁₃H₁₁ClN₄O₂
Molecular Weight	290.70 g/mol
Synonyms	1-(6-Chloro-5-nitro-4-pyrimidinyl)-1,2,3,4-tetrahydroquinoline; 4-(1,2,3,4-Tetrahydroquinolin-1-yl)-6-chloro-5-nitropyrimidine; 6-Chloro-5-nitro-4-(1,2,3,4-tetrahydroquinolin-1-yl)pyrimidine; Quinoline, 1-(6-chloro-5-nitro-4-pyrimidinyl)-1,2,3,4-tetrahydro-; CAS 882276-62-2
EINECS	Contact for details

Quality Control

Our production of 1-(6-Chloro-5-Nitro-4-Pyrimidinyl)-1,2,3,4-Tetrahydroquinoline adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.