Description

N6-(Aminoiminomethyl)-N2-(3-Mercapto-1-Oxopropyl)-L-Lysylglycyl-L-α-Aspartyl-L-Tryptophyl-L-Prolyl-L-Cysteinamide Cyclic (16)-Disulfide Acetate is a high-purity synthetic peptide with a complex cyclic disulfide bridge structure. This compound is of significant interest for advanced research and development in the life sciences, particularly in the study of protein-protein interactions and receptor binding. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on peptide-based therapeutics, diagnostic tools, and biochemical assays.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the discovery and development of novel peptide-based drugs targeting specific biological pathways.
• Biochemical Assay Development: For use as a ligand or substrate in high-throughput screening (HTS) assays to identify enzyme inhibitors or receptor modulators.
• Proteomics and Structural Biology: As a tool compound for studying protein folding, disulfide bond formation, and molecular recognition processes.
• Diagnostic Reagent Manufacturing: Potential use in the synthesis of components for advanced diagnostic kits and biosensors.
• Academic Research: For fundamental studies in medicinal chemistry, peptide synthesis methodology, and molecular pharmacology.

Basic Information

Item	Details
Product Name	N6-(Aminoiminomethyl)-N2-(3-Mercapto-1-Oxopropyl)-L-Lysylglycyl-L-α-Aspartyl-L-Tryptophyl-L-Prolyl-L-Cysteinamide Cyclic (16)-Disulfide Acetate
CAS No.	881997-86-0
Molecular Formula	C41H58N12O12S2 • xC2H4O2
Molecular Weight	~967.1 g/mol (free base)
Synonyms	Cyclic Disulfide Peptide Acetate; [Cys6, Cys16]-Peptide Acetate; Arg-Gly-Asp (RGD) Cyclic Disulfide Peptide Analog; Cyclo(-Cys-Arg-Gly-Asp-Trp-Pro-Cys-) Acetate; c(RGDfK) Disulfide Variant; Integrin-binding Cyclic Peptide; Cyclic RGD Peptide Disulfide; c[RGDfK(SH)]2 Acetate
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and MS for identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing purity, assay, and impurity profiles. Production can be aligned with cGMP guidelines for advanced research and pre-clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store the product desiccated. Allow the vial to warm to room temperature in a dry environment before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC/IC)	1.0 - 3.0 eq
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.