Description

(9H-Fluoren-9-Yl)Methoxy]Carbonyl Tyr(3-Methoxy)-Oh is a specialized, protected amino acid derivative used as a critical building block in solid-phase peptide synthesis (SPPS). This compound matters because it provides precise control over the incorporation of a modified tyrosine residue, enabling the research and development of complex peptides with tailored biological properties. It is primarily needed by pharmaceutical R&D teams, biotech companies, and academic research institutions focused on developing novel therapeutic peptides, peptide hormones, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the automated synthesis of custom peptide sequences.
• Pharmaceutical Research: For the development of peptide-based drug candidates targeting GPCRs, enzymes, and other biological pathways.
• Bioconjugation & Probe Development: Enables the site-specific introduction of a methoxy-tyrosine moiety for labeling or structural modification studies.
• Structure-Activity Relationship (SAR) Studies: Used to investigate the role of tyrosine phosphorylation mimics or modifications on peptide function and stability.
• Academic & Industrial Biochemistry: Serves as a reagent for studying protein-protein interactions and signal transduction mechanisms.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methoxy]Carbonyl Tyr(3-Methoxy)-Oh
CAS No.	881911-32-6
Molecular Formula	C26H23NO6
Molecular Weight	445.46 g/mol
Synonyms	Fmoc-Tyr(3-OMe)-OH; Fmoc-O-methyl-L-tyrosine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-methyl-L-tyrosine; Fmoc-L-Tyrosine(3-OMe); Fmoc-3-Methoxy-L-tyrosine; N-Fmoc-O-methyl-L-tyrosine; (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-(3-methoxyphenyl)propanoic acid
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methoxy]Carbonyl Tyr(3-Methoxy)-Oh is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral integrity. We adhere to relevant industry standards for fine chemicals and can provide material suitable for use under cGMP guidelines for non-GMP early-phase development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	-15.0° to -18.0° (c=1 in DMF)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.