Description

2-(4-Bromo-Phenyl)-4-Chloro-6-Fluoro-Quinazoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core quinazoline scaffold, substituted with halogen atoms at strategic positions, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by pharmaceutical R&D and agrochemical research teams focused on developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Serves as a building block for developing new herbicides and fungicides with enhanced activity.
• Material Science: Used in the research and development of organic electronic materials and advanced polymers.
• Chemical Synthesis: Acts as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Academic & Institutional Research: Employed in universities and research institutes for exploring new heterocyclic chemistry and reaction pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules.

Basic Information

Product Name	2-(4-Bromo-Phenyl)-4-Chloro-6-Fluoro-Quinazoline
CAS No.	881310-87-8
Molecular Formula	C14H7BrClFN2
Molecular Weight	337.57 g/mol
Synonyms	4-Chloro-2-(4-bromophenyl)-6-fluoroquinazoline; 6-Fluoro-2-(4-bromophenyl)-4-chloroquinazoline; 2-(4-Bromophenyl)-4-chloro-6-fluoroquinazoline; Quinazoline, 2-(4-bromophenyl)-4-chloro-6-fluoro-; 881310-87-8; 4-Chloro-6-fluoro-2-(4-bromophenyl)quinazoline
EINECS	Contact for details

Quality Control

Our 2-(4-Bromo-Phenyl)-4-Chloro-6-Fluoro-Quinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.