Description

3,4-Difluoro-5-Methoxybenzaldehyde is a high-purity fluorinated aromatic aldehyde building block, essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorine and methoxy functionalities into complex molecules.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the difluoro-methoxy motif can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved performance and stability.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial laboratories for constructing complex fluorinated aromatic systems and exploring new catalytic reactions.
• Polymer Modification: Acts as a monomer or cross-linking agent for introducing specific functional groups into specialty polymer backbones.

Basic Information

Product Name	3,4-Difluoro-5-Methoxybenzaldehyde
CAS No.	881190-46-1
Molecular Formula	C8H6F2O2
Molecular Weight	172.13 g/mol
Synonyms	5-Methoxy-3,4-difluorobenzaldehyde; 3,4-Difluoro-5-methoxybenzaldehyde; 3,4-Difluoro-5-methoxy-benzaldehyde; Benzaldehyde, 3,4-difluoro-5-methoxy-; 881190-46-1; 5-Methoxy-3,4-difluorobenzaldehyde
EINECS	Contact for details

Quality Control

Our 3,4-Difluoro-5-Methoxybenzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider packaging under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.