Description

L-Leucine, L-Methionyl-L-α-Aspartylglycyl-L-Cysteinyl-L-α-Glutamyl- CAS NO 881188-48-3 is a high-purity, synthetic peptide derivative of significant interest in advanced biochemical research and development. This compound is valued for its role as a specialized building block and model substrate in the study of peptide stability, enzymatic cleavage, and metabolic pathways. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on proteomics, drug discovery, and the development of novel therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and intermediate in the synthesis and analysis of complex peptide-based drug candidates.
• Biochemical Assay Development: Used as a model substrate to study enzyme kinetics, protease activity, and peptide degradation mechanisms.
• Proteomics and Metabolic Studies: Employed in research investigating protein folding, stability, and cellular metabolic pathways involving branched-chain amino acids.
• Academic Research: A key reagent for universities and institutes conducting fundamental research in organic chemistry, biochemistry, and molecular biology.
• Quality Control & Analytical Standards: Functions as a high-purity standard for calibrating analytical instruments like HPLC and mass spectrometers in QC laboratories.

Basic Information

Product Name	L-Leucine, L-Methionyl-L-α-Aspartylglycyl-L-Cysteinyl-L-α-Glutamyl-
CAS No.	881188-48-3
Molecular Formula	C24H41N7O11S2
Molecular Weight	667.75 g/mol
Synonyms	L-Met-L-Asp-Gly-L-Cys-L-Glu-L-Leu; Methionylaspartylglycylcysteinylglutamylleucine; H-Met-Asp-Gly-Cys-Glu-Leu-OH; Leucine, L-methionyl-L-α-aspartylglycyl-L-cysteinyl-L-α-glutamyl-; Peptide M(D)GCEL; 881188-48-3; (S)-2-((S)-2-((S)-2-((S)-2-((S)-2-Amino-4-methylpentanamido)-4-carboxybutanamido)-3-mercaptopropanamido)acetamido)-3-carboxypropanamido)-4-(methylthio)butanoic acid
EINECS	Contact for details

Quality Control

Our L-Leucine, L-Methionyl-L-α-Aspartylglycyl-L-Cysteinyl-L-α-Glutamyl- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for research applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; it is recommended to store under an inert atmosphere such as nitrogen or argon for long-term stability. Keep the container tightly sealed when not in use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.