Description

L-2-Hydroxytryptophan Hydrochloride is a high-purity, non-proteinogenic amino acid derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical chiral building block and a potential precursor for the synthesis of complex bioactive molecules, including novel pharmaceuticals and research probes. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on neuroscience, metabolic studies, and innovative drug discovery programs.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, particularly those targeting neurological pathways.
• Biochemical Research: Used as a standard or reagent in enzymatic studies, metabolic pathway analysis, and neurotransmitter research.
• Precursor for Active Pharmaceutical Ingredients (APIs): Serves as a building block in the multi-step synthesis of more complex, potent drug candidates.
• Neuroscience Studies: Investigated for its role and effects in serotonergic and related biochemical systems within experimental models.
• Reference Standard: Employed in analytical laboratories for method development, validation, and quality control testing via HPLC, LC-MS, or other chromatographic techniques.
• Fine Chemical Synthesis: Utilized in organic synthesis for introducing the tryptophan scaffold with additional hydroxyl functionality into target molecules.

Basic Information

Product Name	L-2-Hydroxytryptophan Hydrochloride
CAS No.	881025-90-7
Molecular Formula	C11H13N2O3•HCl
Molecular Weight	256.69 g/mol (for free base C11H12N2O3)
Synonyms	L-2-Hydroxytryptophan HCl; (2S)-2-Amino-3-(2-hydroxyl-1H-indol-3-yl)propanoic acid hydrochloride; 2-Hydroxy-L-tryptophan hydrochloride; 2-OH-L-Trp HCl; 2-HTP HCl; 1H-Indole-3-propanoic acid, 2-hydroxy-α-amino-, hydrochloride, (αS)-; L-α-Amino-1H-indole-3-propanoic acid, 2-hydroxy-, monohydrochloride
EINECS	Contact for details

Quality Control

Our L-2-Hydroxytryptophan Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. Certificates of Analysis (COA) detailing specific results for each parameter are available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	-30.0° to -35.0° (c=1 in H2O)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.