Description

Benzenamine, 2-Chloro-3-Fluoro-4-Iodo- is a highly functionalized aniline derivative, serving as a critical multi-halogenated building block in advanced organic synthesis. Its precise substitution pattern makes it a valuable scaffold for constructing complex molecules with tailored electronic and steric properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its halogenated aromatic structure.
• Chemical Biology Probes: Serves as a starting point for synthesizing labeled compounds and molecular probes for biochemical and diagnostic applications.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) for constructing biaryl and conjugated systems.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex dyes, pigments, and other performance chemicals.

Basic Information

Product Name	Benzenamine, 2-Chloro-3-Fluoro-4-Iodo-
CAS No.	880652-49-3
Molecular Formula	C6H4ClFIN
Molecular Weight	271.46 g/mol
Synonyms	2-Chloro-3-fluoro-4-iodoaniline; 4-Iodo-2-chloro-3-fluoroaniline; 2-Chloro-3-fluoro-4-iodobenzenamine; Aniline, 2-chloro-3-fluoro-4-iodo-; 880652-49-3; 2-Cl-3-F-4-I-aniline
EINECS	Contact for details

Quality Control

Our production of Benzenamine, 2-Chloro-3-Fluoro-4-Iodo- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the exacting standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging are performed under controlled lighting conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.